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***Gene therapy*** involves modifying a person's own cells to make them resistant to HIV or to enhance their ability to fight the virus. One approach involves extracting cells from a person's immune system, modifying them in the lab, and then infusing them back into the body. These modified cells can then target and destroy HIV-infected cells. A significant area of focus within gene therapy is the use of *CRISPR technology*. CRISPR allows scientists to precisely edit DNA, offering the potential to remove the HIV virus from infected cells or to disable genes that HIV uses to replicate. Several clinical trials are underway to evaluate the safety and efficacy of CRISPR-based therapies in people living with HIV. Early results have been encouraging, with some participants showing a reduction in viral reservoirs. However, challenges remain in ensuring that the gene editing is precise and doesn't have unintended side effects. Researchers are also working on ways to deliver gene therapies more effectively to reach a larger number of infected cells.
